The Effect of pH and Buffer on Oligonucleotide Affinity for Iron Oxide Nanoparticles
Magnetic Fe3O4 nanoparticles (MNPs) have great potential in the nucleic acid delivery approach for therapeutic applications.Herein, the formation of a stable complex of iron oxide nanoparticles with oligonucleotides was investigated.Several factors, such as pH, buffer components, and Matchy Match oligonucleotides sequences, were chosen for binding